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X-WR-CALNAME;VALUE=TEXT:[OPEN]: Springer Lab Special Postdoctoral Fellow Position (2026)
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SUMMARY:[OPEN]: Springer Lab Special Postdoctoral Fellow Position (2026)
DESCRIPTION:<h4 dir="ltr"><span>Position: Special Postdoctoral Fellow in Cell Surface Receptors, Integrin Agonists, and Organoid Biology at Harvard Medical School and Boston Children's Hospital</span></h4><h5 dir="ltr"><span>Join the Lab of Tim Springer</span></h5><p><span>Tim Springer, a leader in integrin biology, invites aspiring scientists to join his lab to advance groundbreaking research at the intersection of integrin signaling, organoid development, and cell surface receptor structure and mechanobiology. A new focus is bioengineering new materials for organoids, with wide-reaching implications for regenerative medicine, stem cell biology, and therapeutic development. This role offers mentorship and unique opportunities to establish a strong scientific foundation for launching an independent research career.</span><br>&nbsp;</p><h5 dir="ltr"><span>About the Role:</span></h5><p dir="ltr"><span>As a Special Postdoctoral Fellow, you will:</span></p><ul><li dir="ltr" data-list-item-id="e3509c89fc782619e56dd880fdd3e8f2f"><span>Pursue cutting-edge research in areas such as:</span><ul><li data-list-item-id="e12143f024a00d1596564effd5effd0b6"><span>Stem Cells and organoids: Develop and apply novel ligands that bind to temperature-dependent gels for stem cell and organoid growth</span></li><li data-list-item-id="e32558c371f4f3f800ee08b18b7a41c65"><span>Cryo-EM: Activation of integrins and TGF-β and ligand binding</span></li><li data-list-item-id="ed942a41d22495019c0b55ea10edd6eae"><span>Mechanobiology: Integrin force transduction in adhesion and TGF-β activation</span></li><li data-list-item-id="e14b1741dfbe2b327c32dad678ca88154"><span>Single Molecules: Utilize advanced techniques including FRET and magnetic tweezers to explore</span></li><li data-list-item-id="e2d92f592b21db9159e00fffc0faf1698"><span>conformational change kinetics and force transmission in integrins and selectins</span></li><li data-list-item-id="eb97f3b3528d3f11c361a8ed8d72129a1"><span>Innovative ReaLiSM: (Receptor and Ligand in Single Molecules) to study receptor-ligand binding dynamics</span></li><li data-list-item-id="e0d24aa8de5c3055c85568ae04930983a"><span>TGF-β Activation: Research localized activation at cell surfaces for new therapeutic targets</span></li></ul></li><li dir="ltr" data-list-item-id="eb17f3bcac72a061ffda7fe52d555e421"><span>Own and Develop Your Project: We encourage candidates to develop new research ideas, which they can carry forward to establish their own labs.</span></li></ul><p dir="ltr"><span>&nbsp;</span></p><h5 dir="ltr"><span>Key Techniques and Approaches:</span></h5><ul><li data-list-item-id="e728f6ff7af1231a108116b6e6403a81f"><span>Organoid and stem cell systems</span></li><li data-list-item-id="ee88422f34088060321c7b352b937adbf"><span>Single-molecule imaging</span></li><li data-list-item-id="ee2f24d84a5e65c786139f850e4990dae"><span>Cryo-EM</span></li><li data-list-item-id="e53ea3644f0bf457c1638283e3d67fb3d"><span>FRET reporters using non-canonical amino acids</span></li><li data-list-item-id="e1a8c9edce27b9114498738f07298b026"><span>Magnetic and laser tweezers</span></li><li data-list-item-id="e01362c5d58da4f62209d29fdfbe13c19"><span>Mechanobiology and therapeutic target discovery</span></li></ul><p dir="ltr"><span>&nbsp;</span></p><h5 dir="ltr"><span>Why Join Us?</span></h5><ul><li data-list-item-id="ecc849ce230c3acb41930cf94f2ae5e9f"><span>Mentorship from Tim Springer, renowned for his pioneering work in integrins and cell biology</span></li><li data-list-item-id="ebb501170e411be448a1409d8dbb42e7a"><span>Work at the frontier of a rapidly expanding area bridging fundamental biophysics and translational biotech</span></li><li data-list-item-id="e2fed54436f01b7550b27435a2c248945"><span>Independence and Growth: Develop projects that will empower your transition to an independent research career</span></li><li data-list-item-id="ea080e73b905837cda71b9750aa0856f1"><span>Collaborative environment at Harvard Medical School and Boston Children’s Hospital</span><br>&nbsp;</li></ul><p dir="ltr"><span>&nbsp;</span></p><h5 dir="ltr"><span>Application Details:&nbsp;</span></h5><p dir="ltr"><span>To apply, please email the following to springer_jobs@crystal.harvard.edu with "Special Postdoctoral Fellow 26 - WS" in the subject line:</span></p><ol><li dir="ltr" data-list-item-id="e018bf0eca609bf41d657efaaa4a9de32"><span>Cover letter (include a brief outline of your project interests)</span></li><li dir="ltr" data-list-item-id="ed8bd540540b947db5df86f7464efa7f3"><span>CV</span></li><li dir="ltr" data-list-item-id="e9a85537937e2f7ec214821e08e18835a"><span>Three references</span></li></ol><p dir="ltr"><span><strong>Salary</strong>: $78,000 annually</span><br><span><strong>Appointment:</strong> 1-year initial term, renewable (multi-year funding)</span><br><span><strong>Start</strong>: Spring/Summer 2026</span><br><span><strong>Visa sponsorship</strong>: Available</span></p><p><em><span>The posted pay range is the Department of Pediatrics’ and Children’s Hospital Pediatric Associates inc. reasonable and good-faith expectation for this pay estimate at the time of posting.&nbsp;</span></em></p><p><em><span>Any base pay offer provided depends on skills, experience, education, certifications, and a variety of other job-related factors. Base pay is one part of a comprehensive benefits package that includes medical/vision/dental coverage, back-up child-care, disability benefits, retirement plans, professional expense accounts, commuter and other employee discounts.</span></em></p><p dir="ltr"><em><span>Qualified applicants will receive consideration without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status, or disability.</span></em></p>
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STATUS:CONFIRMED
DTSTART:20250821T040000Z
DTEND:20260831T035900Z
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