Cell Lines and Antibodies

ANTIBODY

SPECIFICITY

Name
Clone
Species
Isotype
Function
Species
Molecule
CD
Companies with License
References
CBR/49d.1
CBR/49d.1(9F10)
Mouse
IgG1; kappa
 
Human
Integrin alpha4, VLA-4
CD49D
BD Biosciences
Vonderheide, R. H., Tedder, T. F., Springer, T. A., and Staunton, D. E. (1994) Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. J. Cell Biol. 125, 215-222
BioLegend
EBioscience
R&D Systems
Santa Cruz
CBRM1/5
CBR-RM1/5
Mouse
IgG1
Blocking
Human
Activated Mac-1
CD11b
BioLegend
Diamond, M. S., and Springer, T. A. (1993) A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J. Cell Biol. 120, 545-556
eBioscience
Santa Cruz
BD Biosciences (Fisher Scientific)
EXBIO Praha
CBRIC2/2
CBR-IC2/2
Mouse
IgG2a
 
Human
ICAM-2
CD102
Biolegend Santa Cruz
de Fougerolles, A. R., Stacker, S. A., Schwarting, R., and Springer, T. A. (1991) Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. J. Exp. Med. 174, 253-267
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
MorphoSys
Millipore
CBRIC3/1
CBR-IC3/1
Mouse
IgG1
 
Human
ICAM-3
CD50
Biolegend
de Fougerolles, A. R., and Springer, T. A. (1992) Intracellular adhesion molecule-3 and its binding ligands. Center For Blood Research, WO/1992/022323
Millipore
LM2/1
LM2/1.6.11
Mouse
IgG1
 
Human
integrin alphaM, Mac-1
CD11b
Biolegend
Miller, L. J., Schwarting, R., and Springer, T. A. (1986) Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation. J. Immunol. 137, 2891-2900
Santa Cruz
M1/22
M1/22.25.8.HL
Rat
IgM
 
Mouse, Sheep
Forssman Antigen
 
ATCC
Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8, 539-551
ThermoFisher
M1/42
M1/42.3.9.8.HLK
Rat
IgG2a
 
Mouse
H-2
 
Biolegend
Springer, T. A. (1980) Cell-surface differentiation in the mouse. Characterization of "jumping" and "lineage" antigens using xenogeneic rat monoclonal antibodies. in Monoclonal antibodies (Kennett, R. H., McKearn, T. J., and Bechtol, K. B. eds.), Plenum Press, New York. pp 185-217
M1/69
M1/69.16.11.HL
Rat
IgG2b; kappa
 
Mouse
Heat stable antigen
CD24
Biolegend
Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8, 539-551
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
MorphoSys
Miltenyi Biotec
Tonbo Biotech
Millipore
M1/70
M1/70.15.11.5.HL
Rat
IgG2b; kappa
Blocking
Mouse, Human
integrin alphaM, Mac-1
CD11b
ATCC TIB-128
Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8, 539-551
Biolegend
Santa Cruz
eBiosciences (ThermoFisher)
Miltenyi Biotec
EXBIO Praha
Stem Cell Tech Life
Tech Advanced Targeting Systems
M1/75
M1/75.16.4.HLK
Rat
IgG2c
 
Mouse
Heat stable antigen
 
ATCC TIB-127
Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8, 539-551
M1/87
M1/87.27.7.HLK
Rat
IgM; kappa
 
Mouse, Sheep, Human
Forssman Antigen
 
Santa Cruz
Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8, 539-551
BD Biosciences (Fisher Scientific)
M1/89.18
M1/89.18.7.HK
Rat
IgG2b
 
Mouse
common leukocyte antigen (200KD)
CD45
ATCC TIB-124
Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8, 539-551
M1/9.3
M1/9.3.4.HL.2
Rat
IgG2a
 
Mouse
common leukocyte antigen (200KD)
CD45
Santa Cruz
Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8, 539-551
M17/4
M17/4.4.11.9
Rat
IgG2a; kappa
Blocking
Mouse
integrin alphaL, LFA-1
CD11a
ATCC TIB-217
Sanchez-Madrid, F., Davignon, D., Martz, E., and Springer, T. A. (1982) Antigens involved in mouse cytolytic T-lymphocyte (CTL)-mediated killing: functional screening and topographic relationship. Cell. Immunol. 73, 1-11
Biolegend
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
EXBIO Praha
Tonbo Biotech
Millipore
M17/5
M17/5.2
Rat
IgG2b; kappa
Blocking
Mouse
integrin alphaL, LFA-1
CD11a
ATCC TIB-237
Sanchez-Madrid, F., Davignon, D., Martz, E., and Springer, T. A. (1982) Antigens involved in mouse cytolytic T-lymphocyte (CTL)-mediated killing: functional screening and topographic relationship. Cell. Immunol. 73, 1-11
M18/2
M18/2.a.12.7
Rat
IgG2a; kappa
 
Mouse
integrin beta2
CD18
ATCC TIB-218
Sanchez-Madrid, F., Simon, P., Thompson, S., and Springer, T. A. (1983) Mapping of antigenic and functional epitopes on the α and β subunits of two related glycoproteins involved in cell interactions, LFA-1 and Mac-1. J. Exp. Med. 158, 586-602
Biolegend
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
MorphoSys
Miltenyi Biotec
EXBIO Praha
Millipore
M3/38
M3/38.12.8 HL.2
Rat
IgG2a; kappa
 
Mouse
Mac-2, Galectin-3
 
Biolegend
Springer, T. A. (1980) Cell-surface differentiation in the mouse. Characterization of "jumping" and "lineage" antigens using xenogeneic rat monoclonal antibodies. in Monoclonal antibodies (Kennett, R. H., McKearn, T. J., and Bechtol, K. B. eds.), Plenum Press, New York. pp 185-217
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
MorphoSys
Miltenyi Biotec
EXBIO Praha
Millipore
Cedarlane Labs
M3/84
M3/84.6.34
Rat
IgG1; kappa
 
Mouse
Mac-3, LAMP-2 (lysosome associated membrone protein-2)
 
Biolegend
Springer, T. A. (1980) Cell-surface differentiation in the mouse. Characterization of "jumping" and "lineage" antigens using xenogeneic rat monoclonal antibodies. in Monoclonal antibodies (Kennett, R. H., McKearn, T. J., and Bechtol, K. B. eds.), Plenum Press, New York. pp 185-217
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
EXBIO Praha
Millipore
M5/114
M5/114.15.2
Rat
IgG2b; kappa
 
Mouse
Ia, MHC class 2 (I-Ab,d,k and I-E d,k)
 
Biolegend
Davignon, D., Martz, E., Reynolds, T., Kurzinger, K., and Springer, T. A. (1981) Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing. Proc Natl Acad Sci U S A 78, 4535-4539
Santa Cruz
BD Biosciences (Fisher Scientific)
MorphoSys
M5/49
M5/49.4.1
Rat
IgG2a
 
Mouse
Thy-1
 
Millipore
Davignon, D., Martz, E., Reynolds, T., Kurzinger, K., and Springer, T. A. (1981) Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing. Proc Natl Acad Sci U S A 78, 4535-4539
MFR4.B
MFR4.B (9C10)
Rat
IgG2a; kappa
 
Mouse
integrin alpha4, VLA-4
CD49d
Biolegend
Kinashi, T., and Springer, T. A. (1994) Adhesion molecules in hematopoietic cells. Blood Cells 20, 25-44
Santa Cruz
BD Biosciences (Fisher Scientific)
MorphoSys
mIC2/4
mIC2/4 (3C4)
Rat
IgG2a; kappa
Blocking
Mouse
ICAM-2
CD102
Biolegend
Xu, H., Bickford, J. K., Luther, E., Carpenito, C., Takei, F., and Springer, T. A. (1996) Characterization of murine intercellular adhesion molecule-2. J. Immunol. 156, 4909-4914
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
MorphoSys
Millipore
MFR5
MFR5 (5H10)
Rat
IgG2a; kappa
Blocking
Mouse
integrin alpha5, VLA-5
CD49e
Biolegend
Kinashi, T., and Springer, T. A. (1994) Adhesion molecules in hematopoietic cells. Blood Cells 20, 25-44
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
MorphoSys
Miltenyi Biotec
Millipore
Southern Biotechnology Associates
MVCAM.A
MVCAM.A (429)
Rat
IgG2a; kappa
Blocking
Mouse
VCAM-1
CD106
Biolegend
Kinashi, T., and Springer, T. A. (1994) Adhesion molecules in hematopoietic cells. Blood Cells 20, 25-44
Santa Cruz
eBiosciences (ThermoFisher)
BD Biosciences (Fisher Scientific)
MorphoSys
Miltenyi Biotec
EXBIO Praha
Tonbo Biotech
RR 1/1
RR1/1.1.1
Mouse
IgG1
 
Human
ICAM-1
CD54
Miltenyi Biotec
Rothlein, R., Dustin, M. L., Marlin, S. D., and Springer, T. A. (1986) A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 137, 1270-1274
R6.5
R6.5.D6.E9.B2
Mouse
IgG2a
Blocking
Human
ICAM-1
CD54
ATCC HB-9580
Springer TA, et al. Intercellular adhesion molecules, and their binding ligands. US Patent 5,284,931 dated Feb 8 1994
RG11/15
RG11/15.5.4
Mouse
IgG2a; kappa
 
Rat
kappa chain (IgK-1b)
 
BD Biosciences (Fisher Scientific)
Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F. (1982) Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies. Hybridoma l, 257-273
RG11/39
RG11/39.4
Mouse
IgG2b; kappa
 
Rat
IgG1(Fc)
 
BD Biosciences (Fisher Scientific)
Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F. (1982) Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies. Hybridoma l, 257-273
Miltenyi Biotec
RG7/1
RG7/1.30
Mouse
IgG2b; kappa
 
Rat
IgG2a(Fc)
 
BD Biosciences (Fisher Scientific)
Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F. (1982) Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies. Hybridoma l, 257-273
Miltenyi Biotec
RG7/11
RG7/11.1
Mouse
IgG2b; kappa
 
Rat
IgG2b(Fc)
 
BD Biosciences (Fisher Scientific)
Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F. (1982) Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies. Hybridoma l, 257-273
Miltenyi Biotec
RG7/7
RG7/7.6.HL
Mouse
IgG2b; kappa
 
Rat, Hamster
Ig k1b (LEW) light chain
 
BD Biosciences (Fisher Scientific)
Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F. (1982) Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies. Hybridoma l, 257-273
RG7/9
RG7/9.1.HLK
Mouse
IgG2b
 
Rat, Hamster
Ig k light chain
 
BD Biosciences (Fisher Scientific)
Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F. (1982) Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies. Hybridoma l, 257-273
RG9/6
RG9/6.13.HLK
Mouse
IgG2b
 
Rat
IgG2a(Fab')
 
ATCC TIB-167
Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F. (1982) Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies. Hybridoma l, 257-273
TS1/18
TS1/18.1.2.11
Mouse
IgG1
Blocking
Human
integrin b2
CD18
CytoDyn
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
Biolegend
Miltenyi Biotec
TS1/22
TS1/22.1.1.13.3
Mouse
IgG1
Blocking
Human
Integrin aL, LFA-1
CD11a
CytoDyn
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
TS2/16
TS2/16.2.1
Mouse
IgG1
Activating
Human
Integrin B1
CD29
Biolegend
Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., Springer, T. A., and Strominger, J. L. (1984) Glycoproteins of 210,000 and 130,000 M.W. on activated T cells: Cell distribution and antigenic relation to components on resting cells and T cell lines. J. Immunol. 132, 3011-3018
eBiosciences (ThermoFisher)
Miltenyi Biotec
Orbigen
TS2/18
TS2/18.1.1
Mouse
IgG1
 
Human
LFA-2
CD2
Santa Cruz
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
TS2/4
TS2/4.1.1
Mouse
IgG1
No
Human
Integrin aL, LFA-1
CD11a
EMD
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
Millipore
Southern Biotechnology Associates
Biolegend
Proteintech
TS2/7
TS2/7.1.1
Mouse
IgG1
 
Human
Integrin a1, VLA-1
CD49a
Biolegend
Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., Springer, T. A., and Strominger, J. L. (1984) Glycoproteins of 210,000 and 130,000 M.W. on activated T cells: Cell distribution and antigenic relation to components on resting cells and T cell lines. J. Immunol. 132, 3011-3018
Miltenyi Biotec
eBiosciences (ThermoFisher)
Santa Cruz
MorphoSys
TS2/9
TS2/9.1.4.3
Mouse
IgG1
Blocking
Human
LFA-3
CD58
Biolegend
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
Miltenyi Biotec
eBiosciences (ThermoFisher)
Santa Cruz
Proteintech
CKR-7
(Fc fusion protein)
CCR7 (ELC-Fc)
 
IgG1
 
Human, Mouse
CCR7
 
Santa Cruz
 
GARP5
GARP5
Mouse
IgG1
 
Human
GARP/LRRC32
 
Morphic Therapeutics
Wang, R., Zhu, J., Dong, X., Shi, M., Lu, C., and Springer, T. A. (2012) GARP regulates the bioavailability and activation of TGF-β. Mol. Biol. Cell 23, 1129-1139
EXBIO Praha
Tonbo Biotech
 
M139
 
 
 
 
 
 
Santa Cruz
 
M19/23
M19/23
Rat
 
 
Mouse
Mac-1
CD11b
BD Biosciences (Fisher Scientific)
Sanchez-Madrid, F., Simon, P., Thompson, S., and Springer, T. A. (1983) Mapping of antigenic and functional epitopes on the α and β subunits of two related glycoproteins involved in cell interactions, LFA-1 and Mac-1. J. Exp. Med. 158, 586-602
TS1/8
TS1/8
Mouse
IgG1, kappa
 
Human
LFA-2
CD2
Biolegend
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
EXBIO Praha
Proteintech
TS2/16
TS2/16.2.1
Mouse
IgG1
Activating
Human
integrin beta1
CD29
Biolegend
Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., Springer, T. A., and Strominger, J. L. (1984) Glycoproteins of 210,000 and 130,000 M.W. on activated T cells: Cell distribution and antigenic relation to components on resting cells and T cell lines. J. Immunol. 132, 3011-3018
eBiosciences (ThermoFisher)
Miltenyi
Proteintech
CBR LFA1/2
CBR LFA-1/2
Mouse
IgG1
 
Human
integrin b2
CD18
Biolegend
Petruzzelli, L., Maduzia, L., and Springer, T. A. (1995) Activation of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) mimicked by an antibody directed against CD18. J. Immunol. 155, 854-866
TS2/14
TS2/14
Mouse
IgG1
 
Human
LFA-1
CD11a
license status is active
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
TS2/6
TS2/6
Mouse
IgG1
 
Human
LFA-1
CD11a
license status is active
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
TS1/16
TS1/16
Mouse
IgG1
 
Human
HLA-DR
 
license status is active
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
TS1/12
TS1/12
Mouse
IgG1
 
Human
LFA-1
CD11a
license status is active
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
TS1/11
TS1/11
Mouse
IgG1
 
Human
LFA-1
CD11a
license status is active
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493
TS1/2
TS1/2
Mouse
IgG1
 
Human
HLA-DR
 
license status is active
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A. (1982) Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U. S. A. 79, 7489-7493

 

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