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New Research Institute to Transform Protein Science: Q&A with Timothy Springer, Ph.D. [Drug Discovery and Development Magazine]

June 22, 2017

 

The Institute for Protein Innovation (IPI) opened its doors last month on the campus of Harvard Medical School.

Founded by Timothy Springer, Ph.D., Latham Family Professor at Harvard Medical School and Boston Children’s Hospital along with Andrew C. Kruse, Ph.D., Assistant Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, the IPI hopes to bridge the gap between genomes and therapeutics.

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HIRING: Senior Administrative Associate

December 20, 2016

 

Are you interested in being an integral member of a scientific team conducting exciting and innovative research in biology? Dr. Timothy Springer is looking for a highly motivated, detail-oriented candidate to fill the position of Sr. Administrative Associate. This position requires a high level thinker with the ability to multi-task, problem-solve, and work independently and as part of team in support of the Principal Investigator, Assistant Professor, and lab.

JOB PURPOSE:
Provides multi-tasking and high-paced administrative support...

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NEW FEATURE: Dr. Tim Springer on science and entrepreneurship

August 5, 2016

“In academia, it’s often the oddity, the unexpected thing, that becomes publishable; and it’s also the thing people use to start companies.”

Dr. Timothy Springer was recently featured on Vector: Boston Children’s Hospital’s science and clinical innovation blog.

Dr. Springer’s article is a two-part feature: a profile, and a Q&A session.

Read more at:

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NEW PAPER: Force-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases.

April 14, 2015

Jongseong Kim, Nathan E. Hudson, and Timothy A. Springer

Abstract

Mutations in the ultralong vascular protein von Willebrand factor (VWF) cause the common human bleeding disorder, von Willebrand disease (VWD). The A1 domain in VWF binds to glycoprotein Ibα (GPIbα) on platelets, in a reaction triggered, in part, by alterations in flow during bleeding. Gain-of-function mutations in A1 and GPIbα in VWD suggest conformational regulation. We report that force application switches A1 and/or GPIbα to a second state with faster...

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