News

HIRING: Senior Administrative Associate

December 20, 2016

 

Are you interested in being an integral member of a scientific team conducting exciting and innovative research in biology? Dr. Timothy Springer is looking for a highly motivated, detail-oriented candidate to fill the position of Sr. Administrative Associate. This position requires a high level thinker with the ability to multi-task, problem-solve, and work independently and as part of team in support of the Principal Investigator, Assistant Professor, and lab.

JOB PURPOSE:
Provides multi-tasking and high-paced administrative support

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NEW FEATURE: Dr. Tim Springer on science and entrepreneurship

August 5, 2016

“In academia, it’s often the oddity, the unexpected thing, that becomes publishable; and it’s also the thing people use to start companies.”

Dr. Timothy Springer was recently featured on Vector: Boston Children’s Hospital’s science and clinical innovation blog.

Dr. Springer’s article is a two-part feature: a profile, and a Q&A session.

Read more at:

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NEW PAPER: Force-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases.

April 14, 2015

Jongseong Kim, Nathan E. Hudson, and Timothy A. Springer

Abstract

Mutations in the ultralong vascular protein von Willebrand factor (VWF) cause the common human bleeding disorder, von Willebrand disease (VWD). The A1 domain in VWF binds to glycoprotein Ibα (GPIbα) on platelets, in a reaction triggered, in part, by alterations in flow during bleeding. Gain-of-function mutations in A1 and GPIbα in VWD suggest conformational regulation. We report that force application switches A1 and/or GPIbα to a second state with faster

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NEW PAPER: Structure of bone morphogenetic protein 9 procomplex.

March 24, 2015

Li-Zhi Mi, Christopher T. Brown,Yijie Gao, Yuan Tian, Viet Q. Le, Thomas Walz, and Timothy A. Springer

Abstract

Bone morphogenetic proteins (BMPs) belong to the TGF-β family, whose 33 members regulate multiple aspects of morphogenesis. TGF-β family members are secreted as procomplexes containing a small growth factor dimer associated with two larger prodomains. As isolated procomplexes, some members are latent, whereas most are active; what determines these differences is unknown. Here, studies on pro-BMP structures and binding to receptors

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Dr. Timothy Springer receives the 2014 Henry M. Stratton Medal

July 22, 2014
The American Society of Hematology Honors Geraldine P. Schechter, MD, and Timothy Springer, PhD, with 2014 Henry M. Stratton Medal

Published on: July 22, 2014

(WASHINGTON, July 22, 2014) – The American Society of Hematology (ASH) today announced that it will recognize Geraldine P. Schechter, MD, of the Washington Veterans Affairs Medical Center and George Washington University, and Timothy Springer, PhD, of Harvard Medical

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