Springer Lab | Springer Lab

Welcome to the Springer Lab!

We study the molecular and mechanical basis of cell adhesion and signaling, focusing on how integrins and related receptors orchestrate immune, developmental, and disease processes. Using single-molecule tools and organoid systems, we uncover how nanoscale conformational changes and force transmission shape multicellular organization and disease pathogenesis.

News

Tim Springer interviewed for Lasker Foundation's "Ask A Scientist" Podcast

April 14, 2026

Timothy A. Springer elected to the 2025 Class of Fellows [National Academy of Inventors]

December 11, 2025

Timothy A. Springer to receive Protein Society's 2025 Stein & Moore Award [Protein Society]

March 27, 2025

Congratulations Dr. Saket Rahul Bagde, recipient of a 2024 Damon Runyon Cancer Research Foundation Research Fellowship

November 01, 2024

Dr. Bagde was one of four Harvard Medical School researchers to receive Damon Runyon Awards . The four-year fellowship will support Dr. Bagde’s research on integrins and the structural mechanisms governing hemidesmosome assembly and disassembly, providing...

Congratulations Dr. Uriel Lopez-Sanchez, recipient of a 2024 Charles A. King Trust Postdoctoral Research Fellowship

October 01, 2024

Dr. Uriel Lopez-Sanchez was awarded a Charles A. King Trust Postdoctoral Research Fellowship . The two-year grant will support Dr. Lopez-Sanchez’s research on the structural mechanisms underlying the rolling adhesion activity of integrins α4β1 and α4β7...

Congratulations Dr. Aravindabharathi Ramakrishnan, recipient of a 2023 CRI Irvington Postdoctoral Research Fellowship

July 01, 2023

Dr. Ramakrishnan was awarded a 2023 Cancer Research Institute (CRI) Research Fellowship . The three-year grant will support Dr. Ramakrishnan’s research on the mechanism by which integrin ⍺Vβ8 converts the TGF- β1 molecule from its active to its inactive...