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66 results for "Publications"
New Cell Systems publication highlights IPI-led antibody discovery platform
Sean Watson, PhD
Timothy Springer
Tim received his B.A. in Biochemistry from University of California in 1971, his Ph.D. in Molecular Biology and Biochemistry from Harvard in 1976 and did a fellowship with Cesar Milstein in Cambridge, England. He began as Assistant Professor on the Quad...
Adhesion receptors of the immune system
The adhesive interactions of cells with other cells and with the extracellular matrix are crucial to all developmental processes, but have a central role in the functions of the immune system throughout life. Three families of cell-surface molecules...
T cell receptor cross-linking transiently stimulates adhesiveness through LFA-1
Effective interaction between T cells and their targets requires that recognition of specific antigen be coordinated with increased cell-cell adhesion. We show that antigen-receptor cross-linking increases the strength of the adhesion mechanism between...