September 20, 2016
The Springer lab wishes Dr. Nathan Hudson farewell and good luck. Nathan—our former resident biophysicist, Star Wars enthusiast, and certified BBQ judge—is starting his own lab as an Assistant Professor at East Carolina University this fall. During his tenure in the Springer lab, Nathan characterized the force-dependent kinetics of binding and unbinding between the VWF A1 domain and platelet GPIb alpha and received an NRSA postdoctoral fellowship from the NIH to support this work. He also collaborated on functional and structural studies of integrins. We wish Prof. Hudson all the best as he moves on to greener BBQ pastures!
- Lin, F. Y., Zhu, J., Eng, E., Hudson, N. E., and Springer, T. A. (2016) β-subunit binding is sufficient for ligands to open the integrin αIIbβ3 headpiece. J Biol Chem. 291, 4537-4546
- Kim, J.*, Hudson, N. E.*, and Springer, T. A. (2015) Force-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases. Proc. Natl. Acad. Sci. U. S. A. 112, 4648-4653. *Equal contribution.
- Dong, X., Hudson, N. E., Lu, C., and Springer, T. A. (2014) Structural determinants of integrin β-subunit specificity for latent TGF-β. Nat. Struct. Mol. Biol. 21, 1091-1096
Dr. Hudson recreating his favorite molecular interaction. Read more about it in his PNAS publication.