Citation:
Parolin, C., et al. Use of murine CXCR-4 as a second receptor by some T-cell-tropic human immunodeficiency viruses. J. Virol. 72, 2, 1652-1656 (1998).
 | Parolin_1998_14132.pdf | 141 KB |
Abstract:
The human CXCR-4 molecule serves as a second receptor for primary, T-cell-tropic, and laboratory-adapted human immunodeficiency virus type 1 (HIV-1) isolates. Here we show that murine CXCR-4 can support the entry of some of these HIV-1 isolates. Differences between mouse and human CXCR-4 in the ability to function as an HIV-1 receptor are determined by sequences in the second extracellular loop of the CXCR-4 protein.
Notes:
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